Official instructions: https://help.ubuntu.com/community/Wine
Installation:
system > administration > synaptic package manager
find wine
select wine1.2 and install (it will automatically get the dependencies)
Configuration:
terminal > type 'winecfg'
Application Install:
cd /Downloads
type 'wine <executable>', where <executable> is the name of the program to install
Running Application:
open terminal
type 'wine 
Uninstalling Application:
open terminal
type 'wine uninstaller'
